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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMEL1
All Species:
5.15
Human Site:
S269
Identified Species:
10.3
UniProt:
Q495T6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q495T6
NP_258428.2
779
89367
S269
E
Y
Y
F
N
G
G
S
N
R
K
V
R
E
A
Chimpanzee
Pan troglodytes
XP_001150860
781
89158
R271
D
Y
Y
F
N
G
G
R
N
R
K
V
R
E
A
Rhesus Macaque
Macaca mulatta
XP_001105708
750
85452
A241
C
T
G
I
Y
K
E
A
C
T
A
Y
V
D
F
Dog
Lupus familis
XP_546737
807
92419
S297
E
Y
Y
F
N
E
G
S
N
R
K
V
R
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLI3
765
88681
N255
E
Y
Y
F
Q
E
D
N
N
H
K
V
R
K
A
Rat
Rattus norvegicus
P0C1T0
774
89178
D264
R
E
Y
Y
F
K
E
D
S
H
R
V
R
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233077
749
86047
V239
N
G
G
N
Y
Q
R
V
R
E
A
Y
L
Q
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689191
755
86752
N245
D
Y
Y
L
S
D
G
N
Y
K
K
V
R
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511056
849
96515
P342
D
Q
L
Q
Y
A
L
P
S
R
D
Y
Y
L
K
Honey Bee
Apis mellifera
XP_392502
776
89056
A269
Q
L
D
Q
M
Q
V
A
L
P
S
R
D
Y
Y
Nematode Worm
Caenorhab. elegans
O16796
848
97043
T339
R
D
Y
Y
L
N
T
T
L
F
S
S
H
M
T
Sea Urchin
Strong. purpuratus
XP_781407
763
86739
R257
S
S
L
G
I
S
S
R
E
Y
F
L
N
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
50.8
82.6
N.A.
77
77.6
N.A.
N.A.
66.2
N.A.
59.9
N.A.
39
40.5
35
38.1
Protein Similarity:
100
97.1
72
89
N.A.
88.6
88.8
N.A.
N.A.
81.6
N.A.
77.6
N.A.
55.9
59.8
54.1
58.5
P-Site Identity:
100
86.6
0
93.3
N.A.
60
33.3
N.A.
N.A.
0
N.A.
53.3
N.A.
6.6
0
6.6
0
P-Site Similarity:
100
93.3
13.3
93.3
N.A.
73.3
53.3
N.A.
N.A.
6.6
N.A.
80
N.A.
20
13.3
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
17
0
0
17
0
0
0
50
% A
% Cys:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
25
9
9
0
0
9
9
9
0
0
9
0
9
9
0
% D
% Glu:
25
9
0
0
0
17
17
0
9
9
0
0
0
42
9
% E
% Phe:
0
0
0
34
9
0
0
0
0
9
9
0
0
0
17
% F
% Gly:
0
9
17
9
0
17
34
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
17
0
0
9
0
0
% H
% Ile:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
17
0
0
0
9
42
0
0
9
9
% K
% Leu:
0
9
17
9
9
0
9
0
17
0
0
9
9
9
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
9
0
0
9
25
9
0
17
34
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% P
% Gln:
9
9
0
17
9
17
0
0
0
0
0
0
0
9
0
% Q
% Arg:
17
0
0
0
0
0
9
17
9
34
9
9
50
0
0
% R
% Ser:
9
9
0
0
9
9
9
17
17
0
17
9
0
0
0
% S
% Thr:
0
9
0
0
0
0
9
9
0
9
0
0
0
9
9
% T
% Val:
0
0
0
0
0
0
9
9
0
0
0
50
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
42
59
17
25
0
0
0
9
9
0
25
9
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _